(Heraldkeepers via Comtex)

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The parameters considered for scoring of cell line development service providers include experience (in terms of number of years from the time the company was established), sources of cell lines and expression hosts, availability of proprietary or licensed technology, types of gene expression, availability of integrated cell line characterization service, availability of biosimilar cell line development service, availability of genetically edited cell line development service, availability of additional cell line related services and applications of cell lines.


The parameters considered for scoring of cell line characterization service providers include experience, number of cell line sources handled, strength of service portfolio (in terms of number of cell line characterization services offered) and availability of mycoplasma clearance service.





Amongst the players based in Europe having supplier power below 20, FUJIFILM Diosynth Biotechnologies, Polpharma Biologics, ExpreS2ion Biotechnologies, ProteoGenix and Abzena emerged as the leading players in the cell line development domain, according to our proprietary scoring criteria. FUJIFILM Diosynth Biotechnologies uses its proprietary Apollo X[1] platform and pAVEway[2] platform for developing high-yielding (7-10 g/L) CHO cell lines and microbial strains, respectively.[3], [4] It assures the monoclonality of cell lines via the Cell Metric[5] plate and provides integrated cell line characterization tests such as STR profiling and mycoplasma testing.[6] Further, Polpharma Biologics appears to be another competent service provider which strengthened it's portfolio post acquisition of Bioceros and its proprietary platform CHOBC[7] in the year 2016.[8] The company specializes in producing high titre (up to 9 g/L) biosimilar cell lines for preclinical, clinical and commercial purposes.[9]


Further, it is interesting to note that in Europe, SGS, Eurofins Biopharma Product Testing, Texcell and Sartorius Stedim BioOutsource have emerged as the leading players offering cell line characterization services.



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[1] Apollo X(TM) is a trademark of FUJIFILM Diosynth Biotechnologies

[2] pAVEway(TM) is a trademark of FUJIFILM Diosynth Biotechnologies

[3] Source:

[4] Source:

[5] Cell Metric(R) is a registered trademark of Solentim

[6] Source:

[7] CHOBC(R) is a registered trademark of Bioceros

[8] Source:

[9] Source:

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